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CENTRO DE INVESTIGACION DEL CANCER

  1. Identificación y validación de nuevos biomarcadores de enfermedades osteoarticulares

    Actualidad

    Identificación y validación de nuevos biomarcadores de enfermedades osteoarticulares

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  2. Mejora la comprensión del origen del linfoma  folicular y del linfoma difuso de células B grandes.

    Actualidad

    Mejora la comprensión del origen del linfoma folicular y del linfoma difuso de células B grandes.

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  3. Relación entre glucosa y la leucemia linfoblástica aguda de células B

    Actualidad

    Relación entre glucosa y la leucemia linfoblástica aguda de células B

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  4. Biobank

    Actualidad

    Biobank

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  5. La FICUS forma parte de la Red de Unidades de Cultura Científica y de la Innovación (Red UCC+i)

    Actualidad

    La FICUS forma parte de la Red de Unidades de Cultura Científica y de la Innovación (Red UCC+i)

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    meetings

Alberto Martín-Lorenzo

Loss of Pax5 confers the metabolic shift essential for the development of pB-ALL as a result of BCR-ABLp190 susceptibility

04/05/2017 - 04/05/2017
Alberto Martín-Lorenzo
Centro de Investigación del Cáncer (CIC-IBMCC), laboratorio 13,

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Bruno Costa-Silva

Novel cell-cell communication networks in organotropic metastasis

11/05/2017 - 11/05/2017
Bruno Costa-Silva
Champalimaud Centre for the Unknown [Lisboa, Portugal] ,

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Papers

Is Centrosomal Protein 70, a Centrosomal Protein with New Roles in Breast Cancer Dissemination and Metastasis, a Facilitator of Epithelial-Mesenchymal
Lazo PA,
Am. J. Pathol.;2017-Mar;187(3);494-497;28109768

Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.
Valent P, Akin C, Hartmann K, Nilsson G, Reiter A, Hermine O, Sotlar K, Sperr WR, Escribano L, George TI, Kluin-Nelemans HC, Ustun C, Triggiani M, Brockow K, Gotlib J, Orfao A, Schwartz LB, Broesby-Olsen S, Bindslev-Jensen C, Kovanen PT, Galli SJ, Austen KF, Arber DA, Horny HP, Arock M, Metcalfe DD,
Cancer Res.;2017-Mar;();;28254862

Crebbp loss cooperates with Bcl2 over-expression to promote lymphoma in mice.
García-Ramírez I, Tadros S, González-Herrero I, Martín-Lorenzo A, Rodríguez-Hernández G, Moore D, Ruiz-Roca L, Blanco O, Alonso-López D, De Las Rivas J, Hartert K, Duval R, Klinkebiel D, Bast M, Vose J, Lunning M, Fu K, Greiner T, Rodrigues-Lima F, Jiménez R, García Criado FJ, García Cenador MB, Brindle P, Vicente-Dueñas C, Alizadeh A, Sánchez-García I, Green MR,
Blood;2017-Mar;();;28288979

A new functional role uncovered for RASGRF2 in control of nuclear migration in cone photoreceptors during postnatal retinal development.
Jimeno D, Santos E,
Small GTPases;2017-Jan;2154-1256;10.1080/;27221061

Unsupervised Analysis of Array Comparative Genomic Hybridization Data from Early-Onset Colorectal Cancer Reveals Equivalence with Molecular Classifica
Arriba M, García JL, Rueda D, Pérez J, Brandariz L, Nutu OA, Alonso L, Rodríguez Y, Urioste M, González-Sarmiento R, Perea J,
Neoplasia;2017-Jan;1476-5586;S1476-55;27987438

Metabolic gatekeeper function of B-lymphoid transcription factors.
Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M,
Nature;2017-Feb;();;28192788

Reverting p53 activation after recovery of cellular stress to resume with cell cycle progression.
Lazo PA,
Cell. Signal.;2017-Feb;33();49-58;28189587

ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA.
Talamillo A, Grande L, Ruiz-Ontañon P, Velasquez C, Mollinedo P, Torices S, Sanchez-Gomez P, Aznar A, Esparís-Ogando A, Lopez-Lopez C, Lafita C, Berciano MT, Montero JA, Vazquez-Barquero A, Segura V, Villagra NT, Pandiella A, Lafarga M, León J, Martínez-Climent JA, Sanz-Moreno V, Fernandez-Luna JL,
Oncogene;2016-Sep;();;27641332

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility.
Gomez-H L, Felipe-Medina N, Sánchez-Martín M, Davies OR, Ramos I, García-Tuñón I, de Rooij DG, Dereli I, Tóth A, Barbero JL, Benavente R, Llano E, Pendas AM,
Nat Commun;2016-Oct;7();13298;27796301

The expression of Podoplanin is associated with poor outcome in cutaneous squamous cell carcinoma.
Cañueto J, Cardeñoso-Álvarez E, Cosano-Quero A, Santos-Briz A, Fernández-López E, Perez-Losada J, Román-Curto C,
J. Cutan. Pathol.;2016-Nov;();;27859466

Comment on 'Wild-type APC prediction of poor prognosis in microsatellite-stable proximal colorectal cancer differs according to the age of onset'.
Perea J, Arriba M, Rueda D, Sánchez R, García JL, Pérez J, Rodríguez Y, González-Sarmiento R, Urioste M,
Br. J. Cancer;2016-May;114(10);e7;27115472

DNA copy number profiling reveals different patterns of chromosomal instability within colorectal cancer according to the age of onset.
Arriba M, García JL, Inglada-Perez L, Rueda D, Osorio I, Rodríguez Y, Alvaro E, Sánchez R, Fernández T, Pérez J, Hernández JM, Benitez J, González-Sarmiento R, Urioste M, Perea J,
Mol. Carcinog.;2016-May;55(5);705-16;25808986

Sororin loads to the synaptonemal complex central region independently of meiotic cohesin complexes.
Gómez R, Felipe-Medina N, Ruiz-Torres M, Berenguer I, Viera A, Pérez S, Barbero JL, Llano E, Fukuda T, Alsheimer M, Pendas AM, Losada A, Suja JA,
EMBO Rep.;2016-May;17(5);695-707;26951638

C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mec
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez-Carballo A, Gutierrez-Uzquiza A, Martín-Granado V, Ventura JJ, Kazanietz MG, Guerrero C, Porras A,
Oncotarget;2016-Jun;();;27286263

Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes.
Blanco-Gómez A, Castillo-Lluva S, Del Mar Sáez-Freire M, Hontecillas-Prieto L, Mao JH, Castellanos-Martín A, Perez-Losada J,
Bioessays;2016-Jul;38(7);664-73;27241833