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  1. Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

    Actualidad

    Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

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  2. La eliminación simultánea de HRAS y NRAS provoca inmadurez pulmonar, fallo respiratorio y muerte neonatal en ratones

    Actualidad

    La eliminación simultánea de HRAS y NRAS provoca inmadurez pulmonar, fallo respiratorio y muerte neonatal en ratones

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  3. El aumento del estrés mecánico está relacionado con un peor pronóstico del cáncer de pulmón.

    Actualidad

    El aumento del estrés mecánico está relacionado con un peor pronóstico del cáncer de pulmón.

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  4.  A new study identifies proteins regulated by cyclic AMP in the model organism Dictyostelium discoideum.

    Actualidad

    A new study identifies proteins regulated by cyclic AMP in the model organism Dictyostelium discoideum.

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  5. IX PREMIO NACIONAL DE INVESTIGACIÓN EN CÁNCER  “DOCTORES DIZ PINTADO”

    Investigación

    IX PREMIO NACIONAL DE INVESTIGACIÓN EN CÁNCER  “DOCTORES DIZ PINTADO”

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  6. Scientific Seminar Series (2019-2020)

    Actualidad

    Scientific Seminar Series (2019-2020)

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  7. MEETING PROYECTO 0639 IDIAL NET 3 E

    Actualidad

    MEETING PROYECTO 0639 IDIAL NET 3 E

    Proyecto “Red Transfronteriza de Innovación en Diagnóstico Precoz de Leucemia para un envejecimiento saludable” (IDIAL-NET)

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Papers

VRK1 functional insufficiency due to alterations in protein stability or kinase activity of human VRK1 pathogenic variants implicated in neuromotor sy
Martín-Doncel E, Rojas AM, Cantarero L, Lazo PA,
Sci Rep;2019-Sep;2045-2322;10.1038/;31527692

LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL.
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sánchez-García I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS,
Cancer Cell;2019-Sep;1878-3686;S1535-61;31447348

Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory response
Suire S, Baltanás FC, Segonds-Pichon A, Davidson K, Santos E, Hawkins PT, Stephens LR,
J. Leukoc. Biol.;2019-Oct;1938-3673;10.1002/;30720883

Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in .
Ramos-Sáenz A, González-Álvarez D, Rodríguez-Galán O, Rodríguez-Gil A, Gaspar SG, Villalobo E, Dosil M, de la Cruz J,
RNA;2019-Nov;1469-9001;10.1261/;31413149

Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice.
Fuentes-Mateos R, Jimeno D, Gomez C, Calzada N, Fernandez-Medarde A, Santos E,
Cell Death Dis;2019-Nov;2041-4889;10.1038/;31685810

Olaparib and ionizing radiation trigger a cooperative DNA-damage repair response that is impaired by depletion of the VRK1 chromatin kinase.
Campillo-Marcos I, Lazo PA,
J. Exp. Clin. Cancer Res.;2019-May;1756-9966;10.1186/;31101118

Cytosine-5 RNA methylation links protein synthesis to cell metabolism.
Gkatza NA, Castro C, Harvey RF, Heiß M, Popis MC, Blanco S, Bornelöv S, Sajini AA, Gleeson JG, Griffin JL, West JA, Kellner S, Willis AE, Dietmann S, Frye M,
PLoS Biol.;2019-Jun;1545-7885;10.1371/;31199786

Novel ETV6-RUNX1 Mouse Model to Study the Role of ELF-MF in Childhood B-Acute Lymphoblastic Leukemia: a Pilot Study.
Campos-Sánchez E, Vicente-Dueñas C, Rodríguez-Hernández G, Capstick M, Kuster N, Dasenbrock C, Sánchez-García I, Cobaleda C,
Bioelectromagnetics;2019-Jul;1521-186X;10.1002/;31157932

IgG1 B-cell immunity predates IgE responses in epicutaneous sensitization to foods.
Jiménez-Saiz R, Ellenbogen Y, Koenig JFE, Gordon ME, Walker TD, Rosace D, Spill P, Bruton K, Kong J, Monteiro K, Wen J, Tuomanen EI, Kolbeck R, Chu DK, Waserman S, Jordana M,
Allergy;2019-Jan;1398-9995;10.1111/;29790165

The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein.
Zarich N, Anta B, Fernandez-Medarde A, Ballester A, de Lucas MP, Cámara AB, Oliva JL, Rojas-Cabañeros JM, Santos E,
Oncogenesis;2019-Jan;2157-9024;10.1038/;30631038

Factors Regulating microRNA Expression and Function in Multiple Myeloma.
Misiewicz-Krzeminska I, Krzeminski P, Corchete LA, Quwaider D, Rojas EA, Herrero AB, Gutiérrez NC,
Noncoding RNA;2019-Jan;2311-553X;E9;30654527

Profilin-mediated food-induced allergic reactions are associated with oral epithelial remodeling.
Rosace D, Gomez-Casado C, Fernandez P, Perez-Gordo M, Dominguez MDC, Vega A, Belver MT, Ramos T, Vega F, Marco G, de Pedro M, Sanchez L, Arnas MLM, Santaolalla M, Saez MÁ, Benedé S, Fernández-Rivas M, Blanco C, Alvarado MI, Escribese MM, Barber D,
J. Allergy Clin. Immunol.;2019-Feb;1097-6825;S0091-67;29705246

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID.
Rodríguez-Hernández G, Opitz FV, Delgado P, Walter C, Álvarez-Prado AF, González-Herrero I, Auer F, Fischer U, Janssen S, Bartenhagen C, Raboso-Gallego J, Casado-García A, Orfao A, Blanco O, Alonso-López D, Rivas JL, Tena-Dávila SG, Müschen M, Dugas M, Criado FJG, Cenador MBG, Vicente-Dueñas C, Hauer J, Ramiro AR, Sánchez-García I, Borkhardt A,
Nat Commun;2019-Dec;2041-1723;10.1038/;31804490

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.
Gomez-H L, Felipe-Medina N, Condezo YB, Garcia-Valiente R, Ramos I, Suja JA, Barbero JL, Roig I, Sánchez-Martín M, de Rooij DG, Llano E, Pendas AM,
PLoS Genet.;2019-Aug;1553-7404;10.1371/;31437213

Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling.
Jiang X, Lu X, Zhang Y, Lacaria L, Schuchardt BJ, Mikles DC, Magistri M, García-Ramírez I, Sánchez-García I, Farooq A, Verdun RE, Abdulreda MH, Moy VT, Lossos IS,
Blood Adv;2019-Aug;2473-9537;10.1182/;31362927

last announcements

CONTRATO DE TITULADO SUPERIOR PARA SU INCORPORACIÓN AL CIC DE SALAMANCA, LAB. 13.

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CONTRATO DE TITULADO SUPERIOR PARA SU INCORPORACIÓN AL CIC DE SALAMANCA, LAB. 13.

05/12/19

S**OFFER DESCRIPTION: Graduated in Biotecnology with Master in Biology and Clinic of Cancer to work in Cancer Researh Center in Salmananca at: Functional analysis of genes involved in the genesis of childhood leukemia

 

  • Required Education Level: Graduated in Biotecnology with Master in Biology and Clinic of Cancer. Quatlifications higher than 8.0/10.00
  • Skills/Qualifications: molecular and cellular biology, mouse genetics.
  • Specific Requirements: Experience and previous publications will be evaluated in: 1. Study of mutant mice of genes involved in the genesis of childhood leukemia. 2. Analysis by flow cytometry of childhood leukemia in mice. 3. Development of primary cultures of mouse embryonic fibroblasts. 4. Analysis of cancer heterogeneity. 5.Genotyping of mutant mice by PCR and Southern blot.

The candidate selected should be interesting in apply for a Ph Student.

  • Required Languages: Spanish and English.
  • Required Research Experience: Responsible person with initiative, who has advanced knowledge of cell biology, genetics and molecular biology.

TYPE OF CONTRACT : Temporary

JOB STATUS: Full-time

HOURS PER WEEK: 37.5

SALARY: I Colective Agreement FICUS

ENVISAGED JOB STARTING DATE:  January 2020

OFFER STARTING DATE: December 4, 2019.

REFERENCE NUMBER: 19-26-ISGTS

 

Apply for the job position  REF: 19-26-ISGTS  in  http://www.cicancer.org/en/grant-announcement.

 

DEADLINE:          December 18, 2019.

 


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JAE INTRO ICUS 2019

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JAE INTRO ICUS 2019

26/11/19


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