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  • Laboratorio 14

Dr. Rogelio González Sarmiento

CARACTERIZACIÓN DE LOS EVENTOS GENÉTICOS QUE DETERMINAN LA APARICIÓN Y PROGRESIÓN TUMORAL DE CÁNCERES DEL SISTEMA HEMATOPOYÉTICO


Biography

Dr. González-Sarmiento obtained his degree in medicine from the University of Salamanca in 1979. He gained his PhD in medicine at the University of Salamanca in 1985. He has been a specialist in Haematology andDr. González-Sarmiento obtained his degree in medicine from the University of Salamanca in 1979. He gained his PhD in medicine at the University of Salamanca in 1985. He has been a specialist in Haematology and Haemotherapy since 1985. He was awarded a Fullbright fellowship at the Lab. of Medicine and Pathology, Minneapolis Minnesota, USA, where he worked from 1985 to 1987. He then received a grant to return to Spain where he worked at the Department of Medicine of the University of Salamanca from 1988 to 1989. He was also an EMBO fellowship-holder at the Lab. of Molecular Biology, Cambridge Univ., UK, in 1990. Afterwards, he became a tenured professor in medicine (1989-1998). Dr. González-Sarmiento has worked on the study of gene rearrangements and the characterisation of chromosomal translocations in haematologic neoplasms, and has later become involved in the cloning and characterisation of new genes involved in tumour genesis.

 Dr. Rogelio   González Sarmiento
Contact


Dr. Rogelio González
Catedrático, Unidad de Medicina Molecular. Departamento de Medicina, Universidad de Salamanca.
Laboratorio Nº 14

923 294 500
gonzalez(arroba)usal(.)es

Centro de Investigación del Cáncer (Universidad de Salamanca-CSIC)
Campus Universitario Miguel de Unamuno s/n
37007 Salamanca
SPAIN

Areas of Research


-Molecular characterisation of the Ikaros gene in acute B lymphoblastic leukaemias. Development of animal models bearing anomalies in the Ikaros gene.
-Cloning and molecular characterisation of the human Aiolos gene. Study of its possible involvement in diseases.
-Study of molecular anomalies in family and sporadic breast cancer.
-Study of molecular anomalies in CNS tumours.
-Characterisation of molecular alterations in sarcomas of the soft tissues and in peritoneal pseudomyxomas.
-Study of the PATCHED gene in basilomas and Gorlin?s syndrome
-Study of genes that modify susceptibility to cancer.

Projects
  • Caja de Burgos (2012-2012)

    Muerte súbita cardiaca: diagnostico de riesgo genético

  • Instituto de Salud Carlos III (2011-2013)

    Caracterización de alteraciones genéticas y epigenéticas comunes a tumores asociados a síndrome de lynch

  • Junta de Castilla y León (2010-2011)

    Estudio de variants genéticas que predisponen al desarrollo de cáncer de mama familiar en pacientees in mutaciones en BRCA1 O BRCA2

  • JUNTA DE CASTILLA Y LEON (2004-2004)

    IDENTIFICACIÓN DE MUTACIONES EN GENES DE PREDISPOSICIÓN AL CANCER DE MAMA

Publications

(*) Means equal contribution as senior authors.



2017
2016
2015

Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach.

Castellanos-Martín A, Castillo-Lluva S, Sáez-Freire Mdel M, Blanco-Gómez A, Hontecillas-Prieto L, Patino-Alonso C, Galindo-Villardón P, Pérez Del Villar L, Martín-Seisdedos C, Isidoro-García M, Abad-Hernández Mdel M, Cruz-Hernandez JJ, Rodríguez-Sánchez CA, González-Sarmiento R, Alonso-López D, De Las Rivas J, García-Cenador B, García-Criado J, Lee do Y, Bowen B, Reindl W, Northen T, Mao JH, Perez-Losada J, 
Genome Biol.; 2015-; 16(); 40; 25853295


2014
2013

First symposium of ichthyosis experts.

Hernández-Martín A, Torrelo-Fernández A, de Lucas-Laguna R, Casco F, González-Sarmiento R, Vega A, Pedreira-Massa JL, de Unamuno-Pérez P, Larcher F, Arroyo I, Traupe H, 
Actas Dermosifiliogr; 2013-12; 104(10); 877-82; 23375695


2012

Clinical, molecular and biochemical characterization of nine Spanish families with Conradi-Hünermann-Happle syndrome: new insights into X-linked domin

Cañueto J, Girós M, Ciria S, Pi-Castán G, Artigas M, García-Dorado J, García-Patos V, Virós A, Vendrell T, Torrelo A, Hernández-Martín A, Martín-Hernández E, Garcia-Silva MT, Fernández-Burriel M, Rosell J, Tejedor M, Martínez F, Valero J, García JL, Sanchez-Tapia EM, Unamuno P, González-Sarmiento R, 
Br. J. Dermatol.; 2012-03; 166(4); 830-8; 22121851


2011
2010
2009
2008
2007
2006
2005

Albagha OM, Visconti MR, Alonso N, Wani S, Goodman K, Fraser WD, Gennari L, Merlotti D, Gianfrancesco F, Esposito T, Rendina D, di Stefano M, Isaia G, Brandi ML, Giusti F, del Pino-Montes J, Corral-Gudino L, González-Sarmiento R, Ward L, Rea SL, Ratajczak T, Walsh JP, Ralston SH, 
; ; ; ; 23658060

Albagha OM, Wani SE, Visconti MR, Alonso N, Goodman K, Brandi ML, Cundy T, Chung PY, Dargie R, Devogelaer JP, Falchetti A, Fraser WD, Gennari L, Gianfrancesco F, Hooper MJ, Van Hul W, Isaia G, Nicholson GC, Nuti R, Papapoulos S, Montes Jdel P, Ratajczak T, Rea SL, Rendina D, González-Sarmiento R, di Stefano M, Ward LC, Walsh JP, Ralston SH, 
; ; ; ; 21623375

Corral-Gudino L, del Pino-Montes J, García-Aparicio J, Alonso-Garrido M, González-Sarmiento R, 
; ; ; ; 20709566

Albagha OM, Visconti MR, Alonso N, Langston AL, Cundy T, Dargie R, Dunlop MG, Fraser WD, Hooper MJ, Isaia G, Nicholson GC, del Pino Montes J, González-Sarmiento R, di Stefano M, Tenesa A, Walsh JP, Ralston SH, 
; ; ; ; 20436471

Rodríguez-Manotas M, Amorín-Díaz M, Cañizares-Hernández F, Ruíz-Espejo F, Martínez-Vidal S, González-Sarmiento R, Martínez-Hernández P, Cabezas-Herrera J, 
; ; ; ; 17719017

Patents
Group
  •  Dr. Rogelio   González Sarmiento Dr. Rogelio González Sarmiento

    Dr. Rogelio González Sarmiento

    CARACTERIZACIÓN DE LOS EVENTOS GENÉTICOS QUE DETERMINAN LA APARICIÓN Y PROGRESIÓN TUMORAL DE CÁNCERES DEL SISTEMA HEMATOPOYÉTICO

    Telf.:

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    Email: gonzalez@usal.es


    Contact

    Dr. Rogelio González
    Catedrático, Unidad de Medicina Molecular. Departamento de Medicina, Universidad de Salamanca.
    Laboratorio Nº 14

    923 294 500
    gonzalez(arroba)usal(.)es

    Centro de Investigación del Cáncer (Universidad de Salamanca-CSIC)
    Campus Universitario Miguel de Unamuno s/n
    37007 Salamanca
    SPAIN


    Biography

    Dr. González-Sarmiento obtained his degree in medicine from the University of Salamanca in 1979. He gained his PhD in medicine at the University of Salamanca in 1985. He has been a specialist in Haematology andDr. González-Sarmiento obtained his degree in medicine from the University of Salamanca in 1979. He gained his PhD in medicine at the University of Salamanca in 1985. He has been a specialist in Haematology and Haemotherapy since 1985. He was awarded a Fullbright fellowship at the Lab. of Medicine and Pathology, Minneapolis Minnesota, USA, where he worked from 1985 to 1987. He then received a grant to return to Spain where he worked at the Department of Medicine of the University of Salamanca from 1988 to 1989. He was also an EMBO fellowship-holder at the Lab. of Molecular Biology, Cambridge Univ., UK, in 1990. Afterwards, he became a tenured professor in medicine (1989-1998). Dr. González-Sarmiento has worked on the study of gene rearrangements and the characterisation of chromosomal translocations in haematologic neoplasms, and has later become involved in the cloning and characterisation of new genes involved in tumour genesis.

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  • Ruslan Al Ali Ruslan Al Ali

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  • Elisabet González del Portillo Elisabet González del Portillo

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