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Comparison between stem cell renewal and spermatogonial multiplication in humans and mice

Comparison between stem cell renewal and spermatogonial multiplication in humans and mice

Dirk de Rooij

Utrecht University [Utrecht, The Netherlands]

Date: 27/06/2019
Time: 12:30:00
Salón de actos del Centro de Investigación del Cáncer
Alberto Martín Pendás

There are large differences in the spermatogenic process between mice (and most other mammals) and humans. Human spermatogenesis at first sight makes a disorganized impression because the cellular associations that compose an epithelial stage are much smaller in the human than in mice leading to multiple cell associations per tubule section in the human. Importantly, the density of the spermatogonia in the human is very much higher than in mice. These differences