Oesophageal mechanic switch dictates developmental transition towards homeostasis.
María Pilar Alcolea
University of Cambridge [Cambridge, UK]
In order to fully unveil the rules governing epithelial cell behaviour, it is critical to understand the dynamic nature of epithelial cells by exploring their response to situations away from homeostasis. In this study we investigate the cell fate transitions taking place in the mouse squamous oesophageal epithelium from birth until adulthood is reached. The data shows for the first time how the physical changes associated to the fast post-natal growth of the oeso