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Retrieval of endosomal cargo via protein scaffolds.

Retrieval of endosomal cargo via protein scaffolds.

Aitor Hierro

CIC bioGUNE [Vizcaya]

Date: 31/10/2019
Time: 12:30:00
Salón de actos del Centro de Investigación del Cáncer
José María De Pereda

Recycling prevents waste, reduces consumption and saves energy. Living cells constantly recycle proteins and lipids, with a direct impact on nutrient uptake, re-sensitisation to environmental signals, immune surveillance and waste management. Endosomes are key intracellular recycling compartments where the biosynthetic and endocytic pathways intersect. Here, the fate of sorting receptors is directly linked to their selective recruitment into tubulo-vesicular carri