Retrieval of endosomal cargo via protein scaffolds.
CIC bioGUNE [Vizcaya]
Recycling prevents waste, reduces consumption and saves energy. Living cells constantly recycle proteins and lipids, with a direct impact on nutrient uptake, re-sensitisation to environmental signals, immune surveillance and waste management. Endosomes are key intracellular recycling compartments where the biosynthetic and endocytic pathways intersect. Here, the fate of sorting receptors is directly linked to their selective recruitment into tubulo-vesicular carri