Somatic structural variation and cancer.
José Manuel C. Tubio
CIMUS - University of Santiago de Compostela [Santiago de Compostela]
With the advent of next-generation sequencing technologies, we have witnessed a rapid pace of discovery of new patterns of somatic structural variation in cancer genomes, and an attempt to figure out their underlying mechanisms. Some of these mechanisms are associated with particular cancer types, and in some cases are the main cause of the structural mutations that drive the oncogenic process. In this seminar, Dr. Jose Tubio will provide an overview of the patterns of somatic structural vari