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Tissue-specific and time-dependent mechanisms of metastasis.

Tissue-specific and time-dependent mechanisms of metastasis.

Roger Gomis

Institute for Research in Biomedicine (IRB)  [Barcelona]

Date: 14/11/2019
Time: 12:30:00
Salón de actos del Centro de Investigación del Cáncer
Pedro A. Lazo-Zbikowski

Metastatic progression relies on specific biological steps that need to be targeted to improve current therapeutic strategies. Chemotherapy targets high-proliferating tumor cells rather than the low-proliferating metastastic tumor cells, which can then spread from the primary tumor to distant sites, where they resist conventional treatments, proliferate, and cause vital organ failure. Strikingly, different BCa types show distinct metastatic organ tropism, and acqu