Using cryo-electron microscopy to study molecular mechanisms in cancer
Structural Biology Programme, Spanish National Cancer Research Center (CNIO) [Madrid]
Single-molecule Cryo-electron microscopy (cryo-EM) is revolutionising biological research because individual molecules can now be visualised and analysed at atomic resolution, revealing their structure and how they work.
In my talk, I will summarise how cryo-EM works and why we can now achieve high-resolution for non-experts. Then, I will present some of our current work in the lab, studying several macromolecular complexes inv